drugset / Trial / NCT03011996
To Investigate PK and PD of CJ-12420, Clarithromycin, Amoxicillin After Multiple Dose Administration
RandomizedCrossoverOpen-labelBasic science
Summary
Cohort 1 To evaluate the pharmacokinetic interactions of CJ-12420 after multiple oral doses of CJ-12420 given alone or in combination with amoxicillin/clarithromycin in healthy subjects. Cohort 2 To evaluate the pharmacodynamic profiles of CJ-12420 after multiple oral doses of CJ-12420 in combination with amoxicillin/clarithromycin in healthy subjects as compared to an active control group, i.e., pantoprazole in combination with amoxicillin/clarithromycin.
Timeline
- Start
- 2016-05
- Primary completion
- 2017-02
- Completion
- 2017-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AMX | Unknown | 1 g | Oral |
| Subject | CLR | Unknown | 500 mg | Oral |
| Comparator | Pantoprazole | Other / unclassified | 40 mg | — |
| Subject | Tegoprazan | Other / unclassified | 50 mg | Oral |
| Subject | Tegoprazan | Other / unclassified | 100 mg | Oral |
Indications
No indication recorded.