drugset / Trial / NCT03014687
Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions
Phase 4
Recruiting
116 enrolled
St. Joseph's Hospital and Medical Center, Phoenix
The Cleveland Clinic · collabThomas Jefferson University · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
To find out whether oral antibiotics given after transsphenoidal endoscopic surgery for pituitary adenoma improves sinus and nasal symptoms, reduces the incidence of infection (sinusitis), and helps mucosal healing in the nasal passages.
Timeline
- Start
- 2017-07-01
- Primary completion
- 2019-01
- Completion
- 2019-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | cefdinir | Other / unclassified | 300 mg | Oral |
| Subject | trimethoprim/sulfamethoxazole | Unknown | — | Oral |