drugset / Trial / NCT03019536

A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's Disease

NCT03019536

Phase 1 Completed 22 enrolled Eli Lilly and Company
RandomizedParallel-groupDouble-blindBasic science

Summary

The study involves repeated doses of LY3303560 given by infusion for 49 weeks. The study will examine how safe repeated doses of LY3303560 are, whether they cause side effects in participants with mild cognitive impairment or Alzheimer's Disease, and how LY3303560 is handled by the body and acts in the body. This study will last up to 65 weeks, not including screening. Screening is required within 90 days prior to the start of the study.

Timeline

Start
2017-01-31
Primary completion
2019-06-05
Completion
2019-06-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Zagotenemab Monoclonal antibody 70 mg Intravenous
Subject Zagotenemab Monoclonal antibody 210 mg Intravenous
Background Flortaucipir F18 Diagnostic / imaging agent Intravenous
Background florbetapir F 18 Diagnostic / imaging agent Intravenous

Indications