drugset / Trial / NCT03019822

Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing

NCT03019822

Phase 0 Completed 28 enrolled University Hospital, Basel, Switzerland
RandomizedCrossoverQuadruple-blindBasic science

Summary

The study will test the effect of dopamine, serotonin, and direct 5-HT2A receptor stimulation on empathy, mood perception, and amygdala activity to fearful stimuli. In addition, we predict associations between subjective effects/alterations in emotion processing tests and functional imaging (fMRI) activity.

Timeline

Start
2017-02-01
Primary completion
2018-08-11
Completion
2018-09-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Amphetamine Unknown 40.3 mg Oral
Subject LSD Unknown 100 ug Oral
Subject MDMA Unknown 125 mg Oral

Indications

No indication recorded.