drugset / Trial / NCT03025828

Adrenocorticotropic Hormone in Membranous Nephropathy

NCT03025828

Phase 4 Completed 5 enrolled Icahn School of Medicine at Mount Sinai
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the effect of adrenocorticotropic hormone (ACTH, Acthar) on the loss of proteins in the urine (proteinuria) in patients with membranous nephropathy. Acthar is a hormone that stimulates steroid production from small glands above the kidneys. It has direct protective effects on the kidney and is currently approved by the FDA to treat kidney disorders associated with proteins in the urine, but the mechanisms of action are not entirely understood and will be studied in the present trial.

Timeline

Start
2018-03-19
Primary completion
2020-12-16
Completion
2020-12-16

Drugs

EvaluationDrugModalityDoseRoute
Subject Acthar Peptide 80 iu Subcutaneous