The Effect of Oxytocin on the Acquisition and Consolidation of Trauma-Associated Memories

Completed 220 enrolled Charite University, Berlin, Germany Central Institute of Mental Health, Mannheim · collab

RandomizedFactorialTriple-blindBasic science

Summary

The purpose of the study is to examine whether oxytocin and oxytocin receptor gene polymorphism affect the development of intrusive memories, a cardinal symptom of PTSD.

Timeline

Start: 2017-01-15
Primary completion: 2018-06-30
Completion: 2018-06-30

Publications

Schultebraucks K, Maslahati T, Wingenfeld K, Hellmann-Regen J, Kraft J, Kownatzki M, Behnia B, Ripke S, Otte C, Roepke S. Intranasal oxytocin administration impacts the acquisition and consolidation of trauma-associated memories: a double-blind randomized placebo-controlled experimental study in healthy women. Neuropsychopharmacology. 2022 Apr;47(5):1046-1054. doi: 10.1038/s41386-021-01247-4. Epub 2021 Dec 9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Oxytocin	Peptide	24 iu	Intranasal

Indications

No indication recorded.