drugset / Trial / NCT03032848
Vaginal Estrogens Comparative Trial on Pelvic Organ Prolapse Patients
RandomizedParallel-groupDouble-blindSupportive care
Summary
To evaluate the difference of three vaginal estrogens creams comparative with placebo on improvement of hormonal cytology, local and systemic climacteric complaints, as well as its endometrial security.
Timeline
- Start
- 2013-11-26
- Primary completion
- 2016-12-20
- Completion
- 2016-12-26
Publications
- Results Management of symptomatic vulvovaginal atrophy: 2013 position statement of The North American Menopause Society. Menopause. 2013 Sep;20(9):888-902; quiz 903-4. doi: 10.1097/GME.0b013e3182a122c2.
- Taithongchai A, Johnson EE, Ismail SI, Barron-Millar E, Kernohan A, Thakar R. Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women. Cochrane Database Syst Rev. 2023 Jul 11;7(7):CD014592. doi: 10.1002/14651858.CD014592.pub2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Estriol | Unknown | 1 g | Other |
| Comparator | Promestriene | Other / unclassified | 1 g | Other |
| Comparator | conjugated estrogens | Other / unclassified | 1 g | Other |