drugset / Trial / NCT03033784

Autism Oxytocin Brain Project

NCT03033784 ↗

RandomizedCrossoverDouble-blindTreatment

Summary

The main goal of the study is to look at the effects of intranasal oxytocin on the brain in Autism Spectrum Disorder (ASD). Oxytocin is a hormone that exists naturally in the body and the brain, affecting a wide range of social behaviors and emotions. The investigators will study the effects of different treatments (3 doses of oxytocin and one dose of placebo) on brain functional connectivity at rest in patients with ASD, using functional magnetic resonance imaging (fMRI). Investigators also seek to study how the effects of oxytocin treatment can be affected by genetic, immune and environmental factors.

Timeline

Start
2017-05-10
Primary completion
2018-10-03
Completion
2018-10-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxytocin Peptide 8 iu Intranasal
Subject Oxytocin Peptide 24 iu Intranasal
Subject Oxytocin Peptide 48 iu Intranasal

Indications