drugset / Trial / NCT03038776
Recombinant H7 Hemagglutinin Influenza Vaccine Trial
Phase 1
Completed
150 enrolled
Vaxine Pty Ltd
Australian Respiratory and Sleep Medicine Institute · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
Recombinant H7 (rH7) vaccine has been shown to be poorly immunogenic in previous human clinical trials. This study will test approaches to improve the immunogenicity of H7 vaccine, namely use of a three dose regimen, use of a modified H7 HA sequence from which the Tregitope has been removed (rH7m), and inclusion of delta inulin adjuvant adjuvant in the vaccine
Timeline
- Start
- 2017-01
- Primary completion
- 2017-11
- Completion
- 2019-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Panblok H7 | Vaccine | — | Intramuscular |