drugset / Trial / NCT03040024

Delirium Prevention With Ketamine in Ear, Nose, and Throat (ENT) Patients

NCT03040024 ↗

Phase 4 Terminated 71 enrolled Emory University
RandomizedSingle-groupTriple-blindOther

Summary

The goal of this prospective randomized double blinded placebo controlled study is to investigate if a single dose of ketamine in addition to standard anesthesia will reduce the risk of delirium in otolaryngeal cancer patients postoperatively. Ketamine's effect on post-operative pain and opioid use will be measured as well. Electroencephalogram (EEG) will be utilized during the surgical procedure to evaluate its potential as a possible predictive device for delirium.

Timeline

Start
2017-03-17
Primary completion
2020-02-24
Completion
2020-04-24

Outcome

Outcome not reported

Stopped: “Halted due to COVID 19; we believe we have adequate data for analysis”

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketamine Small molecule 0.5 mg/kg Intravenous
Subject Ketamine Small molecule 1 mg/kg Intravenous