drugset / Trial / NCT03047278
Transporters for Organic Cations and Glycemic Control in Patients With Neuropathic Pain.
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This study aimed to investigate the influence of the glycemic control of type 2 diabetes (DM2) and of cetirizine (OCTs inhibitor) on gabapentin kinetics disposition and pharmacodynamics (PK-PD) in patients with neuropathic pain. Thus, non-diabetic patients (Control Group, n=10), patients with controlled diabetes (n=9) and patients with uncontrolled diabetes (n=10), all with neuropathic pain of intensity ≥ 4 in pain visual analog scale (0-10) were investigated.
Timeline
- Start
- 2015-11-01
- Primary completion
- 2018-05-01
- Completion
- 2019-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cetirizine | Other / unclassified | 10 mg | Oral |
| Subject | Gabapentin | Small molecule | 300 mg | Oral |