drugset / Trial / NCT03047525

Study of DC-CTL Combined With CIK for Advanced Solid Tumor

NCT03047525

Phase 1/2 Unknown 200 enrolled Xiaoyi Huang
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Background: Combinations of Dendritic and Cytokine-induced Killer Cells (DC-CIK) and Cytokine-induced Killer Cells (CIK) treatment may enhance the immune response and stop cancer cells from growing. The investigators suppose that DC-CIK combined with CIK treatment will improve the prognosis of advanced solid tumors. Objective: Phase II clinical trial to investigate the efficacy of concurrent chemotherapy with DC-CIK and CIK treatment in patients with treatment-refractory solid tumors. Study treatment: Patients in group A will receive 4 cycles of CIK treatments and 4 cycles of DC-CIK treatments within 8 months. Patients in group B will have no immunotherapy . chemotherapy are available in both groups.

Timeline

Start
2017-02-20
Primary completion
2019-01-01
Completion
2020-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject CIK cells Cell therapy
Subject DC-CIK Cell therapy