drugset / Trial / NCT03050294

Evaluating Treatment Resistant Dermatitis TaroIIR

NCT03050294 ↗

Phase 4 Completed 24 enrolled Wake Forest University Health Sciences
RandomizedParallel-groupOpen-labelTreatment

Summary

Psoriasis and atopic dermatitis are chronic inflammatory disease that account for a significant amount of patients in most dermatological practices. Topical corticosteroid agents are often prescribed for treatment of both these conditions, especially when they are localized rather than wide spread. The development of resistance to treatment is termed tachyphylaxis. Poor adherence, rather than down regulation of receptors, may be the primary cause of tachyphylaxis to topical corticosteroids. The primary objective of the study is to determine, under conditions designed to assure good adherence, whether topical 0.25% desoximetasone spray improves clinical outcomes in patients who have resistant inflammatory skin disease defined by failure of previous topical steroid treatment.

Timeline

Start
2017-02-01
Primary completion
2017-06-01
Completion
2017-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Desoximetasone Small molecule 0.25 % Topical

Indications