drugset / Trial / NCT03058471
Efficacy of Starting Methotrexate Early in Chikungunya Arthritis
RandomizedCrossoverSingle-blindTreatment
Summary
This is a single center, prospective, randomized controlled open label trial with a one sided cross over design to compare the efficacy of initiating Methotrexate(Mtx) in early post Chikungunya induced arthritis (4-12 weeks after onset) with Non Steroidal Anti inflammatory Drugs(NSAID) alone.
Timeline
- Start
- 2016-12
- Primary completion
- 2017-10
- Completion
- 2018-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Methotrexate | Small molecule | 25 mg | — |
| Comparator | Methylprednisolone | Other / unclassified | 80 mg | Intramuscular |
| Comparator | Pantoprazole | Other / unclassified | — | — |