drugset / Trial / NCT03059316

Effect of Hypotensive Anesthesia on the Perfusion Index

NCT03059316

Phase 0 Completed 40 enrolled Cairo University
RandomizedSequentialSingle-blindSupportive care

Summary

Controlled hypotension has been used as a mean of reducing intraoperative blood loss and better visualization of the surgical field in nasal surgeries. Perfusion index has been considered a useful tool for monitoring changes in peripheral perfusion using Masimo set and serum lactate for central perfusion. Many medications were used to induce hypotension. In this study we will compare the effects of tridil and labetalol on the perfusion.

Timeline

Start
2016-06-10
Primary completion
2017-04-10
Completion
2017-04-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator Labetalol Small molecule 0.4 mg/kg
Comparator Labetalol Small molecule 3 mg/kg
Comparator Nitroglycerin Unknown 0.5 ug/kg
Comparator Nitroglycerin Unknown 5 ug/kg

Indications

No indication recorded.