drugset / Trial / NCT03059316
Effect of Hypotensive Anesthesia on the Perfusion Index
RandomizedSequentialSingle-blindSupportive care
Summary
Controlled hypotension has been used as a mean of reducing intraoperative blood loss and better visualization of the surgical field in nasal surgeries. Perfusion index has been considered a useful tool for monitoring changes in peripheral perfusion using Masimo set and serum lactate for central perfusion. Many medications were used to induce hypotension. In this study we will compare the effects of tridil and labetalol on the perfusion.
Timeline
- Start
- 2016-06-10
- Primary completion
- 2017-04-10
- Completion
- 2017-04-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Labetalol | Small molecule | 0.4 mg/kg | — |
| Comparator | Labetalol | Small molecule | 3 mg/kg | — |
| Comparator | Nitroglycerin | Unknown | 0.5 ug/kg | — |
| Comparator | Nitroglycerin | Unknown | 5 ug/kg | — |
Indications
No indication recorded.