Autologous Fecal Microbiota Transplantation to Prevent Antibiotic Resistant Bacteria Colonization

Phase 1 Completed 7 enrolled Microbiome Health Research Institute Boston Medical Center · collab

RandomizedParallel-groupTriple-blindPrevention

Summary

This study, a Randomized controlled trial of Autologous microbiome reconstitution to prevent Colonization by antibiotic rEsistant bacteria (RACE), seeks to investigate the safety, feasibility and the role of autologous fecal microbiota transplantation (FMT) for the prevention of antibiotic resistant bacteria (ARB) through microbiome restoration.

Timeline

Start: 2017-07-10
Primary completion: 2018-12-19
Completion: 2019-06-18

Publications

Liu CK, Seo J, Pravodelov V, Frazier S, Guy M, Concilio K, Lau-Ng R, Brandeis G, Watson J, van der Velde J, Olesen SW, Budree S, Njenga M, Kassam Z, Osman M. Pilot study of autologous fecal microbiota transplants in nursing home residents: Feasibility and safety. Contemp Clin Trials Commun. 2022 Mar 7;27:100906. doi: 10.1016/j.conctc.2022.100906. eCollection 2022 Jun.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Autologous fecal microbiota transplant	Unknown	125 ml	Other

Indications

No indication recorded.