Effect of Rifampicin on the Pharmacokinetics and Pharmacodynamics of Sotagliflozin

Summary

Primary Objective: To evaluate the effects of rifampicin on the pharmacokinetics (PK) of sotagliflozin and its metabolite in healthy male and female subjects. Secondary Objectives: * To assess total 24-hour urinary glucose excretion (UGE) after a dose of sotagliflozin 400 mg, alone and with rifampicin, in healthy male and female subjects. * To assess the safety and tolerability of single dose sotagliflozin with and without rifampicin in healthy male and female subjects.

Timeline

Start

2017-02-27

Primary completion

2017-05-12

Completion

2017-05-12

Drugs

Indications