drugset / Trial / NCT03065062

Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors

NCT03065062

Phase 1 Suspended 75 enrolled Dana-Farber Cancer Institute Pfizer · collab
NaSingle-groupOpen-labelTreatment

Summary

This research study is studying a combination of drugs as a possible treatment for cancer that might have a specific change in the phosphatidylinositol-3 phosphate (PI3K) pathway.

Timeline

Start
2017-02-28
Primary completion
2026-12-31
Completion
2027-01-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Gedatolisib Small molecule 110 mg Intravenous
Subject Palbociclib Small molecule 100 mg Oral