drugset / Trial / NCT03065959

A Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects With Limitations in Mobility

NCT03065959 ↗

RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to investigate the effect of CK-2127107 versus placebo on skeletal muscle fatigue assessed as change from baseline versus 14 days of treatment in sum of peak torque during isokinetic knee extensions. This study will also assess the effects of CK-2127107 on physical performance via a short physical performance battery (SPPB), stair-climb test and 6 minute walk test.

Timeline

Start
2017-06-28
Primary completion
2018-10-10
Completion
2018-10-10

Outcome

Outcome not reported

Stopped: “Lack of efficacy determined at interim analysis”

Drugs

EvaluationDrugModalityDoseRoute
Subject Reldesemtiv Small molecule — Oral

Indications

No indication recorded.