drugset / Trial / NCT03068442

The Role of Large Artery Plaque Imaging Features in Predicting Inflammation and Cognition

NCT03068442

Phase 2 Active not recruiting 45 enrolled Scott Mcnally American Heart Association · collab
NaSingle-groupOpen-labelDiagnostic

Summary

The invesigators propose a clinical study on patients undergoing carotid surgery (endarterectomy). The invesigators will determine carotid artery imaging features associated with (1) vessel wall inflammation, (2) downstream brain inflammation, and (3) cognitive benefit from surgery. This project will uncover links between inflamed carotid plaque and downstream brain inflammation. The invesigators will also determine carotid plaque imaging features predicting cognitive benefit from carotid surgery.

Timeline

Start
2017-02-17
Primary completion
2030-09-10
Completion
2030-09-10

Drugs

EvaluationDrugModalityDoseRoute
Subject 18F-Flutemetamol Diagnostic / imaging agent