drugset / Trial / NCT03072056
A Pharmacokinetic Study of MIN-101 and Its Metabolites in Healthy Subjects to Compare MIN-101 in Poor and Extensive Metabolizers
Non-randomizedCrossoverOpen-labelOther
Summary
* To evaluate the pharmacokinetic (PK) profile of MIN-101 and its metabolites in extensive (EM) and poor (PM) metabolizers * To evaluate the relationship between plasma levels of MIN-101 and changes in QT/QTcF intervals * To evaluate safety and tolerability of MIN-101.
Timeline
- Start
- 2017-01-09
- Primary completion
- 2017-07-07
- Completion
- 2017-07-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Roluperidone | Small molecule | 4 mg | Oral |
| Subject | Roluperidone | Small molecule | 8 mg | Oral |
| Subject | Roluperidone | Small molecule | 16 mg | Oral |
Indications
No indication recorded.