drugset / Trial / NCT03074864

Targeted Treatment With Intercalated Radiotherapy in EGFR-mutant IIIA/IIIB NSCLC

NCT03074864

Phase 2/3 Unknown 90 enrolled Guangdong Provincial People's Hospital
NaSingle-groupOpen-labelTreatment

Summary

The aim of this study is to investigate the efficacy and safety of intercalated combination of erlotinib and radiotherapy for patients with EGFR-mutant, unresectable, locally advanced NSCLC, and to explore a new treatment strategy for this subset. After Induction by erlotinib, local radiotherapy is intercalated, and followed by 24-week erlotinib maintenance.

Timeline

Start
2017-02-27
Primary completion
2019-06-30
Completion
2020-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Erlotinib Small molecule 150 mg Oral