drugset / Trial / NCT03081494

Phase Ib Study of PDR001 in Combination With Regorafenib in Adult Patients With Previously Treated Metastatic Colorectal Cancer

NCT03081494

Phase 1 Completed 10 enrolled Novartis Pharmaceuticals
NaSingle-groupOpen-labelTreatment

Summary

This was a phase Ib study of PDR001 in combination with regorafenib in adult patients with previously treated metastatic microsatellite stable (MSS) colorectal cancer. The study assessed primarily the safety and tolerability of PDR001 in combination with regorafenib.

Timeline

Start
2017-06-09
Primary completion
2019-05-07
Completion
2019-05-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Regorafenib Small molecule 120 mg
Subject Spartalizumab Monoclonal antibody 400 mg

Indications