Modafinil for Freezing of Gait (FOG) in Parkinson's Disease (PD)

Summary

Freezing of gait is a late stage complication of Parkinson's disease in which patients note that their feet feel stuck or glued to the ground. This can lead to imbalance and falls and the secondary complications that can result from falls such as fractures and hospitalizations. While levodopa can help freezing of gait in some patients, it does not help in all, and the dose needed to treat freezing may be limited by side effects of the medications. Currently there are no treatments targeted towards freezing of gait and the goal of this research is to see if Modafinil could be one such drug to help freezing of gait in Parkinson's disease.

Timeline

Start

2017-06-13

Primary completion

2019-11-12

Completion

2019-11-12

Drugs

Indications