drugset / Trial / NCT03093545
Effect of Rabies Immunoglobulin on Immunogenicity of Post-exposure Rabies Vaccination in Obese Patients
Non-randomizedParallel-groupOpen-labelTreatment
Summary
A single center, prospective cohort, open-label study of rabies post exposure program with equine rabies immunoglobulin (ERIG) and purified chick-embryo cell (PCEC) rabies vaccine in WHO category III exposed patients at Siriraj Hospital, Thailand aims to compare serum RVNA responses between obese (BMI \> 30 kg/m2) and normal weight/underweight (BMI \< 25 kg/m2) and to evaluate adverse events occurring after immunization on days 7, 14 and 28.
Timeline
- Start
- 2015-03
- Primary completion
- 2016-10
- Completion
- 2016-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Equine Rabies Immunoglobulin | Protein / enzyme biologic | 40 iu/kg | — |
| Subject | Purified chick-embryo cell rabies vaccine | Vaccine | 1 ml | — |