The Influence of Oxytocin on Socio-communicative Sensitivity

Summary

Oxytocin (OT) is a neuropeptide that acts as a neurotransmitter and neuromodulator in the brain. Previous studies have shown that intranasal administration of OT improves social cognition and behavior (e.g. emotion recognition). In the current study, we want to gain more insight into the underlying mechanisms by which OT influences emotion recognition. More specifically, we will investigate whether intranasal administration of OT enhances the salience of social (compared to non-social) information and whether it increases the neural sensitivity for subtle socio-emotional cues, by recording scalp electroencephalography (EEG) during Fast Periodic Visual Stimulation (FPVS).

Timeline

Start

2016-11-21

Primary completion

2017-05-30

Completion

2017-07-30

Publications

• Tomescu MI, Van der Donck S, Perisanu EM, Berceanu AI, Alaerts K, Boets B, Carcea I. Social functioning predicts individual changes in EEG microstates following intranasal oxytocin administration: A double-blind, cross-over randomized clinical trial. Psychophysiology. 2024 Aug;61(8):e14581. doi: 10.1111/psyp.14581. Epub 2024 Apr 9.

Drugs

Indications

No indication recorded.