drugset / Trial / NCT03104699

A Study of AGEN2034 in Advanced Tumors and Cervical Cancer

NCT03104699

Phase 1/2 Completed 211 enrolled Agenus Inc.
NaSingle-groupOpen-labelTreatment

Summary

This is a 2-part trial: a Phase 1, open-label, dose-escalation study in participants with metastatic or locally advanced solid tumors, with a consecutive Phase 2 expansion to evaluate efficacy in participants with recurrent, unresectable, or metastatic (advanced) cervical cancer that has progressed after a platinum-based treatment regimen.

Timeline

Start
2017-04-11
Primary completion
2022-06-15
Completion
2022-06-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Balstilimab Monoclonal antibody 1 mg/kg Intravenous
Subject Balstilimab Monoclonal antibody 3 mg/kg Intravenous
Subject Balstilimab Monoclonal antibody 6 mg/kg Intravenous
Subject Balstilimab Monoclonal antibody 10 mg/kg Intravenous