drugset / Trial / NCT03107780

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

NCT03107780

Phase 1 Terminated 32 enrolled National Cancer Institute (NCI)
NaSequentialOpen-labelTreatment

Summary

This phase I trial studies the side effects and best dose of navtemadlin in treating patients with glioblastoma (brain cancer) that is newly diagnosed or has come back (recurrent). Navtemadlin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2018-07-09
Primary completion
2025-08-15
Completion
2025-08-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Navtemadlin Small molecule Oral

Indications