drugset / Trial / NCT03108300

Use of Propranolol Hydrochloride in the Treatment of Metastatic STS

NCT03108300

Phase 2 Unknown 50 enrolled Ain Shams University
NaSingle-groupOpen-labelTreatment

Summary

Fifty patients with pathological proof of malignant soft tissue sarcoma will receive Anthracyclin based chemotherapy combined with propranolol 40 mg twice daily. * The primary end point : To assess Progression Free Survival (PFS) * The secondary end points : To assess Overall Survival (OS) and Toxicity Profile

Timeline

Start
2019-08-30
Primary completion
2020-08-30
Completion
2021-08-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Propranolol Small molecule 40 mg
Background Doxorubicin Other / unclassified 60 mg/m2 Other

Indications