Study of AggreGuide A-100 (ADP) Assay

Completed 280 enrolled Aggredyne, Inc.

RandomizedParallel-groupTriple-blindDiagnostic

Summary

Study to evaluate the performance of the AggreGuide A-100 ADP assay for detection of platelet dysfunction caused by P2Y12 inhibitor antiplatelet therapy.

Timeline

Start: 2017-01-09
Primary completion: 2018-06
Completion: 2018-06

Publications

Gurbel PA, Tantry US, Bliden KP, Fisher R, Sukavaneshvar S, Dahlen J, Speros PC. Clinical validation of AggreGuide A-100 ADP, a novel assay for assessing the antiplatelet effect of oral P2Y12 antagonists. J Thromb Thrombolysis. 2021 Jul;52(1):272-280. doi: 10.1007/s11239-021-02498-0. Epub 2021 Jun 18.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Clopidogrel	Small molecule	—	Oral
Subject	Prasugrel	Small molecule	—	Oral
Subject	Ticagrelor	Small molecule	—	Oral

Study of AggreGuide A-100 (ADP) Assay

Summary

Timeline

Publications

Drugs

Indications