drugset / Trial / NCT03111992

Study of Single Agent CJM112, and PDR001 in Combination With LCL161 or CJM112 in Patients With Multiple Myeloma

NCT03111992

Phase 1 Completed 26 enrolled Novartis Pharmaceuticals
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the safety, tolerability, and identify the recommended doses of single agent CJM112, and of CJM112 or LCL161 in combination with PDR001, in patients with relapsed and/or refractory multiple myeloma.

Timeline

Start
2017-12-18
Primary completion
2020-03-02
Completion
2020-03-02

Drugs

EvaluationDrugModalityDoseRoute
Subject CJM112 Monoclonal antibody
Subject LCL161 Small molecule Oral
Subject Spartalizumab Monoclonal antibody

Indications