Allogeneic ADSCs and Platelet-Poor Plasma Fibrin Hydrogel to Treat the Patients With Burn Wounds (ADSCs-BWs)

Phase 1/2 Unknown 20 enrolled A.A. Partners, LLC

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate safety and efficacy of tissue engineered construct based on allogeneic cultured adipose-derived multipotent mesenchymal stromal cells (ALLO-ADSCs) and platelet-poor plasma fibrin hydrogel to treat patients with 2-B and 3- degree burn wounds

Timeline

Start: 2015-03-25
Primary completion: 2018-12-26
Completion: 2018-12-26

Publications

Background Alexaki VI, Simantiraki D, Panayiotopoulou M, Rasouli O, Venihaki M, Castana O, Alexakis D, Kampa M, Stathopoulos EN, Castanas E. Adipose tissue-derived mesenchymal cells support skin reepithelialization through secretion of KGF-1 and PDGF-BB: comparison with dermal fibroblasts. Cell Transplant. 2012;21(11):2441-54. doi: 10.3727/096368912X637064. Epub 2012 Apr 10.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	ALLO-ASCs	Cell therapy	1e+07 cells	—

Indications

No indication recorded.