drugset / Trial / NCT03114540

Single-Dose PK and Safety Study of GBT440 in Subjects With Hepatic Impairment

NCT03114540

Phase 1 Completed 29 enrolled Pfizer
Non-randomizedParallel-groupOpen-labelOther

Summary

A Phase 1, multiple center, nonrandomized, open-label, parallel group study of a single oral dose of GBT440 administered in subjects with mild (Child-Pugh A), moderate (Child-Pugh B), or severe (Child-Pugh C) hepatic impairment disease and healthy subjects with normal hepatic function.

Timeline

Start
2017-03-17
Primary completion
2018-02-28
Completion
2018-03-22

Drugs

EvaluationDrugModalityDoseRoute
Subject Voxelotor Small molecule Oral

Indications

No indication recorded.