drugset / Trial / NCT03118479

Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH)

NCT03118479

Phase 1 Terminated 7 enrolled Massachusetts General Hospital
RandomizedParallel-groupQuadruple-blindBasic science

Summary

The investigators are doing this research study to look at the relationship between testosterone (the main sex hormone in men) and insulin (the hormone that controls blood sugar levels) in men with Idiopathic Hypogonadotropic Hypogonadism (IHH). The investigators hypothesize that normalizing testosterone levels in men with IHH enhances insulin sensitivity, reduces visceral fat, increases lean body mass, and improves the lipid profile.

Timeline

Start
2010-05
Primary completion
2010-09-01
Completion
2010-09-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Anastrozole Other / unclassified 10 mg Oral
Subject Testosterone Small molecule 7.5 g Other

Indications