drugset / Trial / NCT03120130
Study of Amblyomin-X in Advanced Solid Tumor
Phase 1
Suspended
24 enrolled
Uniao Quimica
Buranello e Rodrigues Consultoria em Desenvolvimento Farmacêutico Ltda ME · collab
Non-randomizedSequentialOpen-labelTreatment
Summary
Amblyomin-X is an inhibitor of Factor Xa that also acts as an apoptotic agent for tumor cells. In the case of in vitro assays, Amblyomin-X induces tumor cells to death and does not affect the viability of normal cells. When in vivo assays were performed on mice bearing tumors, treatment with Amblyomin-X caused a significant reduction in tumor mass and number of metastases.
Timeline
- Start
- 2021-02-15
- Primary completion
- 2021-08-20
- Completion
- 2022-05-22
Outcome
Outcome not reported
Stopped: “Delay in the R \& D stage”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amblyomin-X | Unknown | — | Intravenous |