drugset / Trial / NCT03121352

Carboplatin, Nab-Paclitaxel and Pembrolizumab for Metastatic Triple-Negative Breast Cancer

NCT03121352 ↗

Phase 2 Completed 30 enrolled Case Comprehensive Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to see how effective the combination of the two chemotherapy drugs (carboplatin and nab-paclitaxel) are when added to a third drug, pembrolizumab. Pembrolizumab is an investigational (experimental) drug that works by reinvigorating the immune system, allowing it to target and destroy cancer cells. Pembrolizumab is experimental because it is not approved by the Food and Drug Administration (FDA) for this type of breast cancer treatment.

Timeline

Start
2017-05-19
Primary completion
2022-02-20
Completion
2022-05-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule 4.5 unknown Intravenous
Subject Nab-paclitaxel Small molecule 75 mg/m2 Intravenous
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous