drugset / Trial / NCT03122197
Study of Letrozole in Recurrent Gliomas
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine the ability of letrozole to penetrate the blood brain barrier and concentrate in gliomas.
Timeline
- Start
- 2017-05-16
- Primary completion
- 2027-09-01
- Completion
- 2027-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Letrozole | Other / unclassified | 2.5 mg | Oral |
| Subject | Letrozole | Other / unclassified | 15 mg | Oral |
| Subject | Letrozole | Other / unclassified | 20 mg | Oral |
| Background | Temozolomide | Small molecule | 50 mg/m2 | Oral |