drugset / Trial / NCT03127098

QUILT-3.040: ETBX-011 (Ad5 [E1-, E2b-]-CEA(6D)) Vaccine in Combination With ALT-803 (Super-agonist IL-15) in Subjects Having CEA-Expressing Cancer

NCT03127098

Phase 1/2 Terminated 3 enrolled NantCell, Inc.
NaSequentialOpen-labelTreatment

Summary

This is a phase 1b/2 study to evaluate the safety, tolerability, and efficacy of ETBX-011 vaccine used in combination with ALT-803 in subjects with locally advanced or metastatic CEA-expressing cancers whose tumor has recurred after standard-of-care treatment.

Timeline

Start
2017-06-26
Primary completion
2017-12-07
Completion
2017-12-07

Drugs

EvaluationDrugModalityDoseRoute
Subject ETBX-011 Vaccine Subcutaneous
Subject N-803 Protein / enzyme biologic Subcutaneous