drugset / Trial / NCT03132142
Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menthol
RandomizedCrossoverSingle-blindBasic science
Summary
The purpose of this study is to investigate the potential desensitising effects of repeated applications of capsaicin, trans-cinnamaldehyde and L-menthol on thermal, mechanical and chemical sensory stimulations.
Timeline
- Start
- 2017-04
- Primary completion
- 2017-08
- Completion
- 2017-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Capsaicin | Small molecule | 8 % | Topical |
| Subject | Peppermint oil | Other / unclassified | 1 ml | Topical |
| Subject | Peppermint oil | Other / unclassified | 40 % | Topical |
| Subject | Trans-cinnamaldehyde | Unknown | 1 ml | Topical |
| Subject | Trans-cinnamaldehyde | Unknown | 10 % | Topical |