drugset / Trial / NCT03132324

A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease

NCT03132324 ↗

Phase 1 Terminated 12 enrolled Incyte Corporation
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study was to evaluate the safety and tolerability, and the pharmacokinetic and biologic activity of INCB059872 in participants with sickle cell disease.

Timeline

Start
2017-04-20
Primary completion
2018-10-03
Completion
2018-10-03

Outcome

Outcome not reported

Stopped (Business): “This study is terminated due to a business decision not to pursue INCB059782 in Sickle Cell Disease indication.”

Drugs

EvaluationDrugModalityDoseRoute
Subject INCB059872 Small molecule 0.5 mg Oral
Subject INCB059872 Small molecule 1 mg Oral
Subject INCB059872 Small molecule 2 mg Oral

Indications