drugset / Trial / NCT03134378

10 vs 14 Days Triple Therapy : H.Pylori Infection Eradication

NCT03134378

Phase 4 Unknown 73 enrolled Indonesia University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Helicobacter pylori is a bacterium estimated to colonize in the gastrointestinal tract of the half population in the world. Colonization of this bacteria is suspected to be one of the main risk factor for the occurrence of various abnormalities of the upper gastrointestinal tract, such as peptic ulcer and gastrointestinal cancer. The Experts recommend giving triple therapy regimens as first-line eradication therapy for Helicobacter pylori infection. The recommended duration of triple therapy is 10-14 days. However, recent studies suggest triple therapy with longer duration will provide a higher percentage of eradication. This study wanted to show whether 14 days of triple therapy was better than 10 days in Helicobacter pylori eradication.

Timeline

Start
2016-10-03
Primary completion
2017-05-05
Completion
2017-05-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Amoxicillin Other / unclassified 500 mg
Subject Clarithromycin Small molecule 500 mg
Subject Rabeprazole Small molecule 20 mg