Opioid Analgesia for MAB

Phase 4 Completed 172 enrolled Oregon Health and Science University Society of Family Planning · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

Our primary objective will be to determine if a strong opioid, oxycodone, given at a dose recommended for severe pain in addition to ibuprofen decreases maximum pain scores compared to ibuprofen and placebo in women undergoing medical abortion (MAB). Results of this study will help future providers understand whether prescribing opioids are an important adjunct for pain control in women undergoing MAB.

Timeline

Start: 2017-05-01
Primary completion: 2018-05-31
Completion: 2018-05-31

Publications

Colwill AC, Bayer LL, Bednarek P, Garg B, Jensen JT, Edelman AB. Opioid Analgesia for Medical Abortion: A Randomized Controlled Trial. Obstet Gynecol. 2019 Dec;134(6):1163-1170. doi: 10.1097/AOG.0000000000003576.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Oxycodone	Other / unclassified	10 mg	Oral

Indications

No indication recorded.