drugset / Trial / NCT03143543
Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use Disorder
Phase 1
Terminated
171 enrolled
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of Project 2 is to execute phase I functional magnetic resonance imaging (fMRI) studies to assess the effects of lorcaserin on brain target engagement (measured by fMRI brain activation and neural connectivity) in cocaine use disorder (CocUD) subjects and/or opioid use disorder.
Timeline
- Start
- 2015-07
- Primary completion
- 2019-12-06
- Completion
- 2019-12-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lorcaserin | Small molecule | 10 mg | Oral |
| Subject | Lorcaserin | Small molecule | 20 mg | Oral |