drugset

drugset / Trial / NCT03147560

Immunogenicity and Safety Evaluation of Different Sequential Immunization Strategies by Sabin IPV and bOPV in Chinese Infants

NCT03147560 ↗

Phase 4 Completed 528 enrolled Zhejiang Provincial Center for Disease Control and Prevention China National Biotec Group Company Limited · collab

RandomizedParallel-groupSingle-blindPrevention

Summary

The purpose of this study is to evaluate the immunogenicity and safety of different sequential immunization strategies by Sabin IPV and bOPV in Chinese infants.

Timeline

Start: 2017-05-02
Primary completion: 2017-12-30
Completion: 2017-12-30

Publications

He H, Wang Y, Deng X, Yue C, Tang X, Li Y, Liu Y, Yin Z, Zhang G, Chen Z, Xie S, Wen N, An Z, Chen Z, Wang H. Immunogenicity of three sequential schedules with Sabin inactivated poliovirus vaccine and bivalent oral poliovirus vaccine in Zhejiang, China: an open-label, randomised, controlled trial. Lancet Infect Dis. 2020 Sep;20(9):1071-1079. doi: 10.1016/S1473-3099(19)30738-8. Epub 2020 May 19.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sabin-IPV	Vaccine	0.5 ml	—
Subject	bOPV	Vaccine	0.1 ml	—

Indications