Determination the Abuse Potential of Pitolisant in Healthy, Non-Dependent Recreational Stimulant Users

Summary

The purpose of this study is to assess the abuse potential of single doses of pitolisant relative to phentermine HCl and placebo, when administered to healthy, non-dependent, recreational stimulant users.

Timeline

Start

2017-03-15

Primary completion

2017-10-23

Completion

2017-10-23

Publications

• Setnik B, McDonnell M, Mills C, Scart-Gres C, Robert P, Dayno JM, Schwartz JC. Evaluation of the abuse potential of pitolisant, a selective H3-receptor antagonist/inverse agonist, for the treatment of adult patients with narcolepsy with or without cataplexy. Sleep. 2020 Apr 15;43(4):zsz252. doi: 10.1093/sleep/zsz252.

Drugs

Indications