drugset / Trial / NCT03154567
Effects of Stress and Drug-cue Exposure (SCM)
RandomizedCrossoverDouble-blindBasic science
Summary
The purpose of the proposed study to examine the links among stress, craving for marijuana, and marijuana reminders, or "cues". In this study, an agent called yohimbine will be used to produce stress-like responses. Yohimbine is known to cause stress response in studies of alcohol and other substance use disorders. This study intends to show it can be used to cause stress in marijuana users as well.
Timeline
- Start
- 2017-11-01
- Primary completion
- 2023-10-27
- Completion
- 2023-10-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Yohimbine | Small molecule | 0 mg | — |
| Comparator | Yohimbine | Small molecule | 20 mg | — |
| Comparator | Yohimbine | Small molecule | 40 mg | — |