drugset / Trial / NCT03154567

Effects of Stress and Drug-cue Exposure (SCM)

NCT03154567

Phase 1 Completed 12 enrolled Wayne State University
RandomizedCrossoverDouble-blindBasic science

Summary

The purpose of the proposed study to examine the links among stress, craving for marijuana, and marijuana reminders, or "cues". In this study, an agent called yohimbine will be used to produce stress-like responses. Yohimbine is known to cause stress response in studies of alcohol and other substance use disorders. This study intends to show it can be used to cause stress in marijuana users as well.

Timeline

Start
2017-11-01
Primary completion
2023-10-27
Completion
2023-10-27

Drugs

EvaluationDrugModalityDoseRoute
Comparator Yohimbine Small molecule 0 mg
Comparator Yohimbine Small molecule 20 mg
Comparator Yohimbine Small molecule 40 mg

Indications