Pretreatment With Sumatriptan on Cilostazol Induced Headache in Healthy Volunteers

Summary

To develop a pragmatic migraine model the investigators will induce headache in healthy volunteers with a phosphodiesterase inhibitor (cilostazol). The participants will be pre-treated with sumatriptan. If the headache responds to sumatriptan, the model can be used to test new drug candidates.

Timeline

Start

2017-05-23

Primary completion

2017-10-18

Completion

2017-10-18

Publications

• Falkenberg K, Olesen J. Pre-treatment with sumatriptan for cilostazol induced headache in healthy volunteers. J Headache Pain. 2018 Aug 17;19(1):71. doi: 10.1186/s10194-018-0890-y.

Drugs

Indications