drugset / Trial / NCT03165942

Neuroendocrine Response to Oral Alcohol Administration

NCT03165942

RandomizedParallel-groupDouble-blindBasic science

Summary

This study proposes to examine both the peripheral and central nervous system responses when light social drinkers and binge/heavy social drinkers are exposed to oral ethanol. The findings will provide a greater understanding of the brain mechanisms (cerebral blood flow and functional connectivity) underlying the association between stress, cortisol release, heart rate variability, alcohol craving, and alcohol stimulant and sedative effects. This knowledge could be significant in developing new therapies for the treatment of alcoholism.

Timeline

Start
2016-09-08
Primary completion
2018-06-30
Completion
2018-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Alcohol Other / unclassified Oral

Indications