drugset / Trial / NCT03167281
Early Intrapleural TPA Instillation Versus Late
RandomizedParallel-groupOpen-labelTreatment
Summary
Chest tubes are used for air or fluid removal from the pleural space. When a chest tube is placed, it can be hard for the fluid to drain.Tissue plasminogen activator (tPA) and DNase are given through the chest tube to help with draining the fluid. We are doing this research to see if early addition of tPA-DNase immediately after chest tube placement will help with better fluid draining.
Timeline
- Start
- 2017-02-17
- Primary completion
- 2021-03-10
- Completion
- 2021-03-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alteplase | Protein / enzyme biologic | 10 mg | Other |
| Subject | dornase alfa | Protein / enzyme biologic | 5 mg | Other |
Indications
No indication recorded.