drugset / Trial / NCT03169816

Lorcaserin in Combination With XR-Naltrexone for Relapse Prevention in Opioid Use Disorder

NCT03169816

Phase 2/3 Completed 60 enrolled New York State Psychiatric Institute
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study proposes to recruit patients with Opioid Use Disorder (OUD) seeking treatment into our program of outpatient detoxification and naltrexone induction followed by a relapse-prevention treatment with Extended release-naltrexone (XR-NTX) . Eligible participants will be randomly assigned to adjunctive treatment with lorcaserin (N = 40), or placebo (N = 20) with weekly therapy.

Timeline

Start
2017-05-25
Primary completion
2019-08-30
Completion
2019-08-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Lorcaserin Small molecule 10 mg